MyBioSource.com's Anti-Human CD184 (CXCR4) Purified is a Mouse monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
The 12G5 monoclonal antibody specifically bind to human CD184 (CXCR4), a seven-transmembrane G-protein-coupled receptor. It is widely expressed on endothelial cells, hematopietic cells, and also on naïve T cell subsets. CD184 is the receptor for SDF-1 and an alternative receptor for HIV-1. The 12G5 antibody is reported to inhibit SDF-1 induced chemotaxis and calcium influx and some CD4-dependent infections of HIV-1